CanAm is designed to connect major catchment areas across the United States, and at a later stage selected Canadian markets, with the Canary Islands as a strategic Atlantic gateway, extending onward to key destinations across the African continent.
| catchment area | inhabitants | distance | estimated flight time |
| New York | 20,0 million | 5.456 km | 7,0 hrs |
| Los Angeles | 13,0 million | 9.490 km | 10,5 hrs |
| Chicago | 9,5 million | 6.606 km | 8,1 hrs |
| Oakland | 7,7 million | 9.723 km | 10,6 hrs |
| Houston | 7,1 million | 6.515 km | 9,1 hrs |
| Washington DC | 6,2 million | 5.795 km | 7,5 hrs |
| Atlanta | 6,0 million | 6.517 km | 8,0 hrs |
| Boston | 4,9 million | 5.215 km | 6,6 hrs |
| Seattle | 4,0 million | 8.982 km | 10,0 hrs |
| Cape Town | 4.5 million | 7.732 km | 9.5 hrs |
| Johannisburg metro | 6.6 million | 7.588 km | 9.3 hrs |
| Abuja | 4+ million | 3.055 km | 4.2 hrs |
| Toronto | 6,4 million | 5.910 km | 6,9 hrs |
| Montreal | 4,2 million | 5.434 km | 7,0 hrs |
| Vancouver | 2,6 million | 8.884 km | 9,8 hrs |